Familial macular defects.

THE description of individual disorders of the macula by various names has led to confusion. Several familial and hereditary macular diseases have been classified under the title of heredo-macular degeneration. In this category is Best's disease, which is described as a familial congenital macular defect. This is a rare condition, characterized by retention of good central vision and lack of progression of the lesions. Varying degrees of abnormality of the macula have been noted in different members of the same family, the clinical appearances resembling those described in Best's disease (congenital macular and paramacular atrophic defect).